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Cake day: July 9th, 2023

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  • Everyone is talking about dominant and recessive genes, so I just want to clarify a couple things.

    The way your body directly uses genes is as a blueprint to construct proteins. Your cells are always producing proteins from the genes in all your chromosomes. It has complex ways of regulating how much of each it produces, but your body doesn’t care what chromosome it’s coming from. Once an embryo is fertilized, there’s really no distinction between “mom” chromosomes or “dad” chromosomes, as far as the embryo and its protein machinery are concerned.

    “Dominant” and “recessive” characterization is about how those proteins affect your body at the macro scale, not whether your body actually uses the gene and produces its proteins – it always does that. For example, brown hair is a dominant trait, and blonde is recessive. But this is because producing any amount of brown pigment will make your hair brown, regardless of what other pigments you’re making, simply because it’s darker. Literally the same as combining blonde and brown paint. It has nothing to do with whether the genes are actually being expressed – the brown hair gene doesn’t stop the blonde hair gene from making its pigments.










  • 100% on the “lots of missing 'how’s” point. You skipped the “ban lobbying” one, which is probably the second biggest “how” after the gerrymandering.

    Lobbying is not some official policy or process. Senators don’t have “lobbying hours.” Lobbying is basically just “being at lunches and parties that politicians are at.” Unless you’re proposing Congress not be allowed to go out in public and live as secluded monks, I don’t see how you “abolish” it…







  • Now you’ll have a zillion users trying to install software in ways that violate all the assumptions that NixOS operates on, but which are still tightly coupled to your NixOS config. Now updates to your system, or even seemingly unrelated config changes (through some transitive dependency chain) can easily break that software.

    So now we’ve basically removed half the advantages that motivate Nix/OS in the first place, and when stuff breaks it will look like it’s Nix’s fault, even if it isn’t.

    On the other hand, nixpkgs is already the most comprehensive repository of system software out there, and for 99% of packages Nixifying it is pretty trivial. Hell, my NixOS config does that for 3 different GitHub repos right inline in my config.nix