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Joined 1 year ago
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Cake day: June 30th, 2023

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  • I have an Astell & Kern SR25 MKII DAP (digital audio player) and I use it quite frequently. The sound quality far surpasses what my phone can produce when connected to any of my speakers or headphones.

    It plays FLAC files and any other audio file type you can think of. And it acts as an offline music library when needed (64 GB of memory plus a 1TB microSD).

    The better the headphones/speakers I use, the more it outshines anything coming out of my other electronic devices. I use it almost every day.


  • You are saying that sucralose (or a metabolite thereof) could alkylate DNA - and theoretically proteins too - correct? Like what sulfur mustard gas does?

    I did a quick search and couldn’t find any papers demonstrating a mechanism of action for that, although I skimmed a few that postulated that a dichlorinated hydrolysis product might be the true carcinogenic agent. Do you know of any studies that demonstrate that the alkylation can happen, either in vitro or (ideally) in vivo? Or maybe some better search terms to use, that could be my issue…

    I am truly curious about this, I never knew the chemical structure of sucralose until I read your comment and subsequently looked it up.